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We report a case of an acute ST-segment elevation myocardial infarction in a patient with conventional cardiac threat elements using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, probably secondary to high-dose testosterone. The affected person underwent profitable percutaneous intervention of the proper coronary artery. Physicians and sufferers should concentrate on the medical penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a part of endothelial dysfunction has been proposed, which may contribute to irregular vessel reactivity.

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Unfortunately, the info on the use of excessive dose anabolic steroids in people are mainly offered as case stories or small studies that lack adequate control teams. In addition, the data available in the literature doesn’t account for the steroid type or dose, as neither may be recognized. Patients also may be taking concomitant stimulants, such as ephedra, which can confound data and the potential for opposed occasions. It is likely that the frequency of cardiac events is underreported in the medical literature. Supraphysiologic doses of anabolic-androgenic steroids , which include greater than 30 pure and synthetic derivatives of testosterone, might cause a large spectrum of clinical sequalae.

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